Yes, you can work from home. I’ve been doing it for almost 8 yrs now. (80% at home except for the occasional team meeting or client on-site meeting). I work in web consulting and we have a virtual model. In California - there are a LOTof freelancers who work from hom and many companies in the US are allowing their employess to work from home several days a week.

The downside? Surprisingly, after many years I am starting to feel a bit isolated and longing for the group dynamics that an office brings! I’m not alone because co-working spaces are cropping up everywhere that allow you to rent a desk and work in a team environment. http://coworking.pbwiki.com/